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Literature summary extracted from

  • Yang, B.; Bhattacharyya, S.; Linhardt, R.; Tobacman, J.
    Exposure to common food additive carrageenan leads to reduced sulfatase activity and increase in sulfated glycosaminoglycans in human epithelial cells (2012), Biochimie, 94, 1309-1316.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.4 Homo sapiens P34059
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.6.4 Caco-2 cell
-
 Homo sapiens
-
3.1.6.4 colonocyte
-
 Homo sapiens
-
3.1.6.4 intestinal epithelium
-
 Homo sapiens
-
3.1.6.4 mammary epithelial cell
-
 Homo sapiens
-
3.1.6.4 MCF-10A cell
-
 Homo sapiens
-
3.1.6.4 MCF-7 cell
-
 Homo sapiens
-
3.1.6.4 NCM-460 cell
-
 Homo sapiens
-
3.1.6.4 T-47D cell
-
 Homo sapiens
-
3.1.6.4 T-84 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.4 4-methylumbelliferyl beta-D-galactoside 6-sulfate + H2O
-
 Homo sapiens 4-methylumbelliferyl beta-D-galactoside + sulfate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.6.4 galactose-6-sulfatase
-
 Homo sapiens
3.1.6.4 GALNS
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
3.1.6.4 Homo sapiens enzyme activity but not protein content declines after lambda-carrageenan exposure (0.001 mg/l for 48 h) down